Quantification of liver T1rho has gained interest in liver pathological study. Traditional fitting method requires acquisition of multiple T1rho-weighted images and it can be affected by respiratory motion. We propose a physics-informed self-supervised mapping method by taking only one T1rho-weighted image to do the mapping. Our preliminary experimental results show that our method has the potential to outperform the traditional multi-TSL acquisition method, particularly in the scenario of free-breathing MRI scan.
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