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Abstract #3193

Overall survival analysis of esophageal squamous cell carcinoma using MRI-based radiomics features

Yun Liu1, Chenglong Wang1, Funing Chu2, Jinrong Qu2, Xu Yan3, and Guang Yang1
1Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China, 2Department of Radiology, The Affiliated Cancer Hospital of Zhengzhou University &Henan Cancer Hospital, Zhengzhou, China, 3MR Scientific Marketing, Siemens Healthineers, Shanghai, China


A total number of 439 patients with esophageal squamous cell carcinoma (ESCC) were enrolled in this study. All patients scanned using StarVIBE sequences. We split the data randomly into training and independent test cohort in a ratio of 7 to 3. We proposed a method for feature selection to find the most useful features for survival analysis. The radiomics score combined with clinical variables achieved the highest consistency in the prediction of disease-free survival (DFS) with a C-index value of 0.682 in the test cohort and overall survival (OS) with a C-index value of 0.691 in the test cohort.

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