Abstract #3313

Direct Signal Control combined with dynamic, Fast Online Customized (FOCUS) parallel transmit excitation pulses for TSE at 7 Tesla

Jürgen Herrler¹, Jonathan Endres¹, Raphael Tomi-Tricot^2,3,4, Patrick Liebig⁵, Rene Gumbrecht⁵, Christian Richard Meixner⁶, Andreas Maier⁷, Arnd Dörfler¹, Shaihan Malik^3,4, and Armin Michael Nagel^6,8

¹Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ²MR Research Collaborations, Siemens Healthcare Limited, London, United Kingdom, ³Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, ⁴Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, ⁵Siemens Healthcare GmbH, Erlangen, Germany, ⁶Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁷Department of Computer Science, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁸Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Synopsis

Direct Signal Control with Variable Excitation and Refocusing (DiSCoVER) was combined with a dynamic, Fast Online-Customized (FOCUS) parallel transmit excitation pulse for a 3D TSE sequence using an 8Tx/32Rx head RF coil at 7 Tesla. DSC could improve the signal, mainly in the cerebellum region compared to CP mode. FOCUS excitation pulses achieve better FA and phase homogeneity than static pTx pulses (standardly used in DiSCoVER). Combining a FOCUS excitation pulse with DiSCoVER-optimized refocusing pulses, led to signal gain across the echoes, which was evaluated in simulations for 132 subjects. Universal and individual DiSCoVER-refocusing pulses showed comparable performance.

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