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Abstract #3313

Direct Signal Control combined with dynamic, Fast Online Customized (FOCUS) parallel transmit excitation pulses for TSE at 7 Tesla

Jürgen Herrler1, Jonathan Endres1, Raphael Tomi-Tricot2,3,4, Patrick Liebig5, Rene Gumbrecht5, Christian Richard Meixner6, Andreas Maier7, Arnd Dörfler1, Shaihan Malik3,4, and Armin Michael Nagel6,8
1Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 2MR Research Collaborations, Siemens Healthcare Limited, London, United Kingdom, 3Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, 4Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, 5Siemens Healthcare GmbH, Erlangen, Germany, 6Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 7Department of Computer Science, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 8Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Synopsis

Direct Signal Control with Variable Excitation and Refocusing (DiSCoVER) was combined with a dynamic, Fast Online-Customized (FOCUS) parallel transmit excitation pulse for a 3D TSE sequence using an 8Tx/32Rx head RF coil at 7 Tesla. DSC could improve the signal, mainly in the cerebellum region compared to CP mode. FOCUS excitation pulses achieve better FA and phase homogeneity than static pTx pulses (standardly used in DiSCoVER). Combining a FOCUS excitation pulse with DiSCoVER-optimized refocusing pulses, led to signal gain across the echoes, which was evaluated in simulations for 132 subjects. Universal and individual DiSCoVER-refocusing pulses showed comparable performance.

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