Abstract #3321

Functional and structural connectomes of subthalamic nucleus subregions in living humans using 7 Tesla MRI

Maria Guadalupe Garcia Gomar^1,2, Kavita Singh¹, Simone Cauzzo^1,3,4, and Marta Bianciardi¹

¹Brainstem Imaging Laboratory, Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States, ²Escuela Nacional de Estudios Superiores, Juriquilla, Universidad Nacional Autónoma de México, Querétaro, Mexico, ³Sant'Anna School of Advanced Studies, Institute of Life Sciences, Pisa, Italy, ⁴Research Center E. Piaggi, University of Pisa, Pisa, Italy

Synopsis

The subthalamic nucleus (STh) plays a crucial role in the basal ganglia movement-related circuit and it is involved in movement disorders such as Parkinson’s disease, dystonia, and chorea, among others. Its study in living humans is challenging due to limited resolution and contrast in conventional MRI. Previous work developed an in-vivo atlas of two STh subregions based on their fractional anisotropy properties. With the goal of characterizing their function and connectivity, in the present study, we evaluated the functional and structural connectivity of these STh subregions using 7 Tesla MRI and tested their preferential connectivity towards associative or motor regions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.