The subthalamic nucleus (STh) plays a crucial role in the basal ganglia movement-related circuit and it is involved in movement disorders such as Parkinson’s disease, dystonia, and chorea, among others. Its study in living humans is challenging due to limited resolution and contrast in conventional MRI. Previous work developed an in-vivo atlas of two STh subregions based on their fractional anisotropy properties. With the goal of characterizing their function and connectivity, in the present study, we evaluated the functional and structural connectivity of these STh subregions using 7 Tesla MRI and tested their preferential connectivity towards associative or motor regions.
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