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Abstract #3323

Detecting longitudinal dynamic functional connectivity changes using multiband multi-echo fMRI in high school football athletes

Alexander D. Cohen1, Michael D. McCrea2,3, and Yang Wang1
1Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, 2Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States, 3Neurology, Medical College of Wisconsin, Milwaukee, WI, United States

Synopsis

Repetitive head impact exposure (RHIE) during contact sports may have damaging neurocognitive effects. In this study, we investigated longitudinal changes in dynamic functional connectivity (dFNC) using multiband multi-echo (MBME) fMRI in high school football players over the course of two seasons. Four recurring connectivity states were identified. A greater total number of dFNC changes were observed over two seasons compared to over the course of one season. Changes across all four states were only observed in the two-season comparison. These preliminary results suggest that RHIE may lead to accumulated effects in functional connectivity patterns.

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Keywords