Abstract #3457

Assessment of T1, T2, and T1ρ Values of Knee Cartilage and Menisci in Healthy Subjects using 3T MRI: A Preliminary Study

Ralph Zeitoun¹, Chikara Noda¹, Bharath Ambale-Venkatesh¹, Yoshimori Kassai², João A C Lima¹, and Chia-Ying Liu²

¹Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States, ²Canon Medical Systems Corporation, Otawara, Japan

Synopsis

Efforts have been focused on early detection of osteoarthritis using MRI. Our study reports T1, T1ρ and T2 values for knee cartilage and menisci in normal subjects using 3T MRI, and evaluates associations with age, gender, and BMI. We found that WB-FC had higher T1 and lower T2 values than LWB-FC, and WB-FC had higher T1 values in females. T1 values of WB-FC and LM were associated with age, and T1ρ values of WB-FC were associated with BMI. Our study presents novel data on T1 mapping, reinforcing the utility of MRI as a potential tool for early detection of osteoarthritis.

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