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Abstract #3498

Magnetic Resonance Spectroscopy Spectral Registration with Deep Learning

David Ma1, Hortense Le1, Scott Small2,3,4, and Jia Guo2,5
1Department of Biomedical Engineering, Columbia University, New York, NY, United States, 2Department of Psychiatry, Columbia University, New York, NY, United States, 3Department of Neurology, Columbia University, New York, NY, United States, 4Taub Institute Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, United States, 5Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, United States

Synopsis

Deep learning is an effective image processing approach that has been enthusiastically adopted in Magnetic Resonance Spectroscopy (MRS). Methods such as multilayer perceptrons (MLP) and convolutional neural networks (CNN) have been applied to frequency and phase correction (FPC) to help resolve frequency and phase shifts that arise in MRS. However, both methods need to be trained separately with frequency and phase offsets to perform FPC. In this study, we aim to introduce a spectrum registration technique using CNNs that perform simultaneous correction of both frequency and phase shifts of single voxel MEGA-PRESS MRS simulated data.

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Keywords