We propose an efficient, densely connected network to synthesize unacquired DW-volumes from other acquired DW-directions and b=0 mm2/s volumes, allowing acceleration of high-angular DWI shell acquisition by skipping some DW-directions altogether.
For training, we used a high-quality dataset of 20 HCP subjects with 90 DW-directions per subject at both b=1000 mm2/s and 3000 mm2/s. 40 HCP subjects were used for validation. 30 DW-directions were selected for input to reconstruct the other 60 missing target DW-directions.
Comparison with a linear-interpolation benchmark show improved fidelity of synthesized DW-volumes and FOD maps to a gold standard acquisition, for both b-values.
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