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Abstract #3666

Diffusion kurtosis imaging with multiple quantitative parameters for predicting microsatellite instability status in endometrial carcinoma

Wan Dong1, Shifeng Tian1, Lihua Chen2, and Ailian Liu2
1Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, 2the First Affiliated Hospital of Dalian Medical University, Dalian, China

Synopsis

Immunohistochemistry is considered the most common method to determine the MSI status of EC, but this method is usually performed after surgery. Here, diffusion kurtosis imaging (DKI) with multiple quantitative parameters was used to predict microsatellite instability (MSI) status of endometrial carcinoma (EC). Results showed that there were good efficiency of DKI to distinguish MSI status of EC (The AUC of MK, Ka, MD, and Dr values was 0.763,0.729,0.731, 0.748, respectively).

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