Abstract #3678

Quantitative Susceptibility Mapping as an Alternative to CT for Localizing Gold Intraprostatic Fiducial Markers

Ashley Wilton Stewart^1,2, Jonathan Goodwin^3,4, Simon Daniel Robinson^2,5,6, Kieran O’Brien^1,2,7, Jin Jin^1,2,7, Markus Barth^1,2,8, and Steffen Bollmann^1,2,8

¹ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, St Lucia, Australia, ²Centre for Advanced Imaging, The University of Queensland, St Lucia, Australia, ³Department of Radiation Oncology, Calvary Mater Hospital, Newcastle, Australia, ⁴School of Information and Physical Sciences, University of Newcastle, Newcastle, Australia, ⁵High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria, ⁶Department of Neurology, Medical University of Graz, Graz, Austria, ⁷Siemens Healthcare Pty Ltd, Brisbane, Australia, ⁸School of Information Technology and Electrical Engineering, The University of Queensland, St Lucia, Australia

Synopsis

Gold fiducial markers (FMs) for prostate radiotherapy are commonly localized using Computed Tomography (CT), though interest in MR-only workflows is growing. One current limitation with magnitude-based MR-only workflows is the ability to distinguish FMs from blood products and calcifications because all appear as signal voids. Quantitative Susceptibility Mapping (QSM) separates sources based on their susceptibility, and may be a potential solution. We apply the QSMxT pipeline to gradient-echo images of a prostate cancer patient with FMs and a calcification. We found that QSM provided a contrast that could differentiate the FMs from calcifications to a degree comparable to CT.

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