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Abstract #3699

A new radiomic tool based on apparent diffusion coefficient to predict the pathological grade of Bladder Cancer

Danyan Li1, Cheng Wang1, Chuanqi Sun2, Jie Meng1, Jilei Zhang3, Chengyu Ding3, Zijian Bian3, and Bing Zhang1
1department of radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China, 2Department of Biomedical Engineering, Guangzhou Medical University, Guangzhou, China, 3Philips Healthcare, Shanghai, China

Synopsis

The present study tried to develop a new radiomics tool based on apparent diffusion coefficient to predict the pathological grade of Bladder cancer (BCa). The results demonstrate that the radient boosting classifier (GBC) achieved the best effect in distinguishing pathological low or high grade of bladder cancer. And GBC also shows the best accuracy when we added the arch bridge sign on MRI as a new feature. This classification performance may suggest that the proposed method is a promising approach for preoperatively evaluating pathological grade in bladder cancer, which is very important for the choice of clinical treatment options.

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Keywords