This study aimed to investigate the feasibility of T2 mapping in predicting the response to chemoradiation (CRT) for patients with local advanced rectal cancer (LARC). Thirty-five LARC patients were measured with T2 mapping before-, during- and after-CRT. Resultant T2 values during- and after-CRT, and the T2 decrease ratio of before- to during-CRT were correlated significantly with tumor regression grade. Compared to poor responders, good responders showed lower T2 during- and after-CRT and higher T2 decrease ratio of before- to during-CRT. Therefore, quantitative T2 mapping may be useful for predicting the response to CRT for LARC patients.
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