Abstract #3742

A preliminary investigation of radiomics-based diffusion kurtosis imaging differences between glioblastoma and solitary brain metastasis

Eryuan Gao¹, Guohua Zhao¹, Huiting Zhang², Ankang Gao¹, Xiaoyue Ma¹, Jie Bai¹, Xu Yan², Yusong Lin³, Guang Yang⁴, and Jingliang Cheng¹

¹department of magnetic resonance imaging, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²MR Scientific Marketing, Siemens Healthcare, Shanghai, China, ³the School of Software, Zhengzhou University, Zhengzhou, China, ⁴Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China

Synopsis

The differentiation of glioblastomas from solitary brain metastases by using routine magnetic resonance imaging (MRI) alone presents a challenge. As a representative of diffusion MRI technology, diffusion kurtosis imaging (DKI) can closely reflect the real situation of water molecule movement in tumor tissues. We speculate that DKI radiomics is superior to routine MRI radiomics in distinguishing GBMs from SBMs. We developed a series of radiomics models of DKI parameter maps and routine MRI to compare their performance. Finally, several independent parameters models perform well in distinguishing two tumors. The combined DKI radiomics model obtained the best performance.

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