A preliminary investigation of radiomics-based diffusion kurtosis imaging differences between glioblastoma and solitary brain metastasis
Eryuan Gao1, Guohua Zhao1, Huiting Zhang2, Ankang Gao1, Xiaoyue Ma1, Jie Bai1, Xu Yan2, Yusong Lin3, Guang Yang4, and Jingliang Cheng1
1department of magnetic resonance imaging, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2MR Scientific Marketing, Siemens Healthcare, Shanghai, China, 3the School of Software, Zhengzhou University, Zhengzhou, China, 4Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China
The differentiation of glioblastomas from solitary brain metastases by using routine magnetic resonance imaging (MRI) alone presents a challenge. As a representative of diffusion MRI technology, diffusion kurtosis imaging (DKI) can closely reflect the real situation of water molecule movement in tumor tissues. We speculate that DKI radiomics is superior to routine MRI radiomics in distinguishing GBMs from SBMs. We developed a series of radiomics models of DKI parameter maps and routine MRI to compare their performance. Finally, several independent parameters models perform well in distinguishing two tumors. The combined DKI radiomics model obtained the best performance.
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