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Abstract #3827

Pulmonary Compliance Imaging Using Hyperpolarized Gas MRI

Ming Zhang1, Haidong Li1, Hongchuang Li1, Xiuchao Zhao1, Xiaoling Liu1, Yeqing Han1, Xianping Sun1, Xin Lou2, Chaohui Ye1, and Xin Zhou1
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences- Wuhan National Laboratory for Optoelectronics, Wuhan, China, 2Department of Radiology, Chinese PLA General Hospital, Beijing, China


Pulmonary compliance is generally measured using ventilator and esophageal balloon in clinical practice, and only global compliance could be obtained. In this study, we proposed a method for imaging pulmonary compliance using hyperpolarized (HP) 129Xe MRI. Lung compliance derived by HP 129Xe MRI could be used for quantifying the injuries caused by fibrosis in rats.

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