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Abstract #3851

Amide Proton Transfer Imaging of Bladder Cancer at 3 T: A Preliminary Study

Fang Wang1, Yun Xu1, Yong-Sheng Xiang1, Peng Wu2, Ai-Jun Shen1, and Pei-Jun Wang1
1Tongji Hospital, School of Medicine, Tongji University, Shanghai, China, 2Philips Healthcare, Shanghai, China

Synopsis

Amide proton transfer (APT) imaging is an emerging chemical exchange saturation transfer (CEST)-based MRI technique that is sensitive to mobile proteins and peptides in tissue and has drawn considerable attention in the field of cellular and molecular imaging. In the present work, our result demonstrates that it is feasible to use APT imaging for Bladder Cancer (BCa) and it has shown great potential for bladder cancer imaging, thus opening new research avenues in this field.

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