Abstract #3884
Quantitative susceptibility mapping of early myelination in the posterior limb of internal capsule in neonates
Brian Ma1, Lara Bartels1,2, Christian Kames1,2, Yuting Zhang3, Alexander Weber1,4, and Alexander Rauscher1,2,4,5
1UBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada, 2Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 3Department of Radiology, Children's Hospital of Chongqing Medical University, Chongqing, China, 4Division of Neurology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada, 5Department of Radiology, University of British Columbia, Vancouver, BC, Canada
Synopsis
We performed quantitative susceptibility mapping (QSM) of the posterior limb of internal capsule (PLIC) in human neonates. As the PLIC is one of the earliest structures to myelinate, it is clearly visible as a hypointense structure on QSM. This work investigates the potential as a marker for brain health in neonates. There were no significant differences in magnetic susceptibility of the PLIC between healthy controls, injured preterm, and injured term neonates.
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