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Abstract #3949

iMPI – first real-time imaging with a human-sized interventional Magnetic Particle Imaging scanner

Patrick Vogel1, Martin A Rückert1, Teresa Reichl1, Johanna Günther1, Christoph Greiner1, Liana Mirzojan1, Alexander von Böhn1, Thomas Kampf2, Thorsten A. Bley3, Volker C. Behr1, and Stefan Herz3
1Experimental Physics 5 (Biophysics), University of Würzburg, Würzburg, Germany, 2Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Würzburg, Germany, 3Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany

Synopsis

In this work a first human-sized Magnetic Particle Imaging (MPI) scanner designed and specifically engineered for experimental (cardio)vascular interventions is presented.

Based on a novel open design implementing the so called traveling wave MPI approach, the open iMPI system provides imaging of Tracers based on superparamagnetic iron oxide nanoparticles (SPIONs) with high sensitivity, optimal patient handling and would even allow hybrid imaging of magnetic tracers within gold standard x-ray based interventional angiography systems.

In initial experiments, the feasibility of a human-sized interventional MPI scanner with real-time data reconstruction and image visualization is demonstrated.

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Keywords