Transcytolemmal water exchange in prostate manifest via DCE-MRI and DWI kurtosis imaging
Xin Li1, Ryan P Kopp2,3, Eric M Baker1, Brendan Moloney1, William D. Rooney1, Charles S Springer1, Fergus V Coakley4, and Mark G. Gartotto2,3
1Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States, 2Portland VA Medical Center, Portland, OR, United States, 3Urology, Oregon Health & Science University, Portland, OR, United States, 4Diagnostic Radiology, Oregon Health & Science University, Portland, OR, United States
Transcytolemmal water exchange effects are quantified with SSM-DCE MRI and DWI kurtosis imaging with b-values up to 2000 s/mm2. The two-dimensional scatter plot of the unidirectional cellular water efflux rate constant (kio) and the diffusion kurtosis (K) shows good separation between lesion and normal appearing prostate tissue.
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