Measuring placental perfusion can provide important information about its function. Arterial Spin Labeled (ASL) MRI is a non-contrast perfusion imaging method particularly suitable in pregnancy as it does not require an exogenous contrast. We performed a preliminary assessment of placental perfusion in pregnant subjects, both normal and with CHTN, at 16-20 week and 24-28 week gestational ages. Perfusion reduction was observed in all 5 normal subjects and in 75% (12 of 16) of the subjects with CHTN. This could provide important information about perfusion changes during pregnancy and can serve as a precursor for a larger-scale longitudinal study in CHTN.
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