Advanced neuroimaging capabilities enabled by the MAGNUS (ultra-high performance head gradient) system was leveraged in this study to assess subject-specific microstructural changes with acute and chronic mild traumatic brain injury. MAGNUS allows for a four-fold increase in maximum gradient-amplitude compared to current clinical whole-body scanners and enables identification of new imaging biomarkers for improved detection of microstructural changes in the brain. We present an outlier analysis approach that allows study of microstructure differences in individual subjects rather than solely on a group basis. Preliminary results demonstrate identification of several white-matter regions in patient groups that differ from healthy controls.
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