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Abstract #4108

A High RF Bandwidth Diffusion Preparation for Diffusion Weighted Imaging Near Metallic Implants

Philip Kenneth Lee1,2, Daehyun Yoon2, Jesse Kerr Sandberg2, Shreyas Vasanawala2, and Brian Andrew Hargreaves1,2,3
1Electrical Engineering, Stanford University, Stanford, CA, United States, 2Radiology, Stanford University, Stanford, CA, United States, 3Bioengineering, Stanford University, Stanford, CA, United States

Synopsis

There is no widely adopted clinical protocol for diffusion weighted imaging near metal since the commonly used EPI trajectory fails completely due to distortion from off-resonance. We combine the magnetization prepared, stimulated echo diffusion preparation with 3D MSI encoding to enable volumetric diffusion weighted imaging near metal in clinically feasible times. Imaging time is reduced by a factor of 2× with high RF bandwidth root-flipped Shinnar-Le Roux refocusing pulses since spectral coverage can be maintained with fewer excitations. Joint design of the excitation and refocusing pulses reduces B1 sensitivity.

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