The retina has highly structured laminar organization, with two separate blood supplies, the retinal and the choroidal blood flow layers. Retinal MRI has generally used a single thick 2D slice. Extension to 3D retinal MRI is difficult due to the curvature of the eye and limited SNR at the needed high resolution. A new acquisition strategy for MRI of curved objects was developed, in which high-resolution is acquired perpendicular to the retina but with low-resolution tangent to the retina. This approach gave significant gains in SNR and provided laminar resolution of the retinal and choroidal blood flow in 3D.
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