Preoperative prediction of microvascular invasion in hepatocellular cancer using computation modeling of interstitial fluid pressure
Liyun Zheng1,2, Lifang Wu3, Chun Yang3, Ruofan Sheng3, Yongming Dai2, and Mengsu Zeng1,3
1Shanghai Institute of Medical Imaging, Shanghai, China, 2United Imaging Healthcare, Shanghai, China, 3Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China
Microvascular invasion (MVI) is a well-known major prognostic factor of hepatocellular carcinoma (HCC). Unlike macrovascular invasion, which can be easily identified via imaging before treatment, microvascular invasion (MVI) is visible only at microscopy. This study developed a new method for the noninvasive interstitial fluid pressure (IFP) measurement in HCC patients. Our results revealed that MVI status can be predicted by this IFP model preoperatively,
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