Abstract #4216

Preoperative prediction of microvascular invasion in hepatocellular cancer using computation modeling of interstitial fluid pressure

Liyun Zheng^1,2, Lifang Wu³, Chun Yang³, Ruofan Sheng³, Yongming Dai², and Mengsu Zeng^1,3

¹Shanghai Institute of Medical Imaging, Shanghai, China, ²United Imaging Healthcare, Shanghai, China, ³Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China

Synopsis

Microvascular invasion (MVI) is a well-known major prognostic factor of hepatocellular carcinoma (HCC). Unlike macrovascular invasion, which can be easily identified via imaging before treatment, microvascular invasion (MVI) is visible only at microscopy. This study developed a new method for the noninvasive interstitial fluid pressure (IFP) measurement in HCC patients. Our results revealed that MVI status can be predicted by this IFP model preoperatively,

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