Abstract #4223

High-Resolution Diffusion-Weighted Imaging of Hepatocellular Carcinoma (HCC)

Hui Zhang¹, Chengyan Wang², Peng Wu³, Huazheng Shi⁴, Weibo Chen³, and He Wang¹

¹Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ²Human Phenome Institute, Fudan University, Shanghai, China, ³Philips Healthcare, Shanghai, China, ⁴Shanghai Universal cloud imaging dignostic center, Shanghai, China

Synopsis

Diffusion-weighted imaging (DWI) is a widely used tool for diagnosing hepatocellular carcinoma (HCC). However, clinical routine liver DWI suffers from poor spatial resolution, severe geometry distortion, and image blurring since single-shot (SSH) echo-planar imaging (EPI) is used. Here we proposed an efficient solution for clinical high-resolution whole-liver DWI. The efficacy and generalization capability of the method were validated on healthy volunteers and HCC patients.

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