Quantitative Evaluation of Crohn's Disease Using Native T1 Mapping: A Feasibility Study
Daisuke Morimoto-Ishikawa1,2, Tomoko Hyodo3, Yoriaka Komeda4, Hiroyuki Fukushima1, Yu Ueda5, Keizou Miyagoshi1, Shigeyoshi Saito2, and Kazunari Ishii3
1Radiology Center, Kindai University Hospital, Osakasayama City, Japan, 2Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita City, Japan, 3Department of Radiology, Kindai University, Osakasayama City, Japan, 4Department of Gastroenterology and Hepatology, Kindai University, Osakasayama City, Japan, 5Philips Japan, Tokyo, Japan
We investigated the usefulness of native T1 mapping using a modified look-locker inversion recovery (MOLLI) sequence, which can be used to evaluate Crohn's disease (CD). The nativeT1 value was measured by setting an ROI on the intestinal wall of the nativeT1 map containing the short-axis image of the intestine. Simple endoscopic activity score in CD (SES-CD) was used as the reference standard for evaluating CD activity. A strong correlation was found between native T1 value and the SES-CD (r = 0.83; p = 0.001).
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