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Abstract #4235

Low Variance ADC Technique Reduces Bias of Kidney ADC Values

Qiao Li1, Xiance Zhao2, and Peng Wu2
1Radiology, Jiangsu Provincial People’s Hospital,Nanjing Medical University, Nanjing, China, 2Philips Healthcare, Shanghai, China


Low variance (LOVA) ADC technique could compensate for gradient linearity errors, delivering consistent ADC values with high accuracy in large FOV. This work aims to investigate if gradient nonlinearity bias can be corrected in evaluating the ADC values of kidney using LOVA ADC technique. Our results verified that the corrective effect exists in both health volunteers and patients with common kidney diseases. With the corrected ADC, we could better estimate the unbiased difference between marginal lesions and central lesions, to better predict biological behavior of tissues and provide useful information for diagnosis and treatment.

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