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Abstract #4254

The feasibility of using magnetic resonance elastography for differentiation of benign and malignant solid pancreatic masses

Jiejun Chen1, Dingxia Liu1, Shujie Zhang1, Wei Sun1, Yinglong Guo1, Yunfei Zhang2, Yongming Dai2, and Xiuzhong Yao1
1Zhongshan Hospital affiliated to Fudan University, Shanghai, China, 2Central Research Institute, United Imaging Healthcare, Shanghai, China


Magnetic resonance elastography (MRE) is an emerging functional MR technique. Pancreatic ductal adenocarcinoma (PDAC), as one of the most lethal diseases, accounts for 85–90% of all malignant pancreatic tumors. Histologically, PDAC is a hard mass characterized by a marked desmoplastic reaction and build-up of fibrotic tissues. In this study, we aim to evaluate the usefulness of 2D spin-echo echo-planar-imaging (SE-EPI) MRE for differentiation of solid pancreatic masses. Our results showed that compared with benign pancreatic masses, PDAC demonstrated higher mass stiffness and stiffness.

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