Quantitative Evaluation of Liver Function using Normalized Gadoxetic Acid Concentration in Hepatobiliary Phase
Shoma Eitoku1, Yasuhiro Fujiwara2, and Motohira Mio3
1Graduate School of Health Sciences, Kumamoto University, Kumamoto, Japan, 2Department of Medical Image Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 3Department of Radiology, Fukuoka University Chikushi Hospital, Fukuoka, Japan
The purpose of this study was to clarify whether gadoxetic acid concentration in the hepatic focal area at hepatobiliary phase (CHep), normalized by dose (normalized CHep), could be used as an index for quantitative liver function assessment. In severe liver dysfunction, a moderate correlation was observed between gadoxetic acid concentration and dose. Normalized CHep with bias correction based on the dose of gadoxetic acid may be used as an index of liver function, especially in the stratification of severe liver dysfunction.
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