A risk stratification scoring system for predicting axillary lymph node metastasis in breast cancer using multiparametric MRI
Xiaofeng Chen1, Jiada Yang1, Nina Fan1, Zhiqi Yang1, Ruibin Huang2, Yue Li1, Cuixia Wan1, Junhao Gong1, Yuting Liao3, Guijin Li4, Mengzhu Wang5, Fengyan Cheng1, Xiangguang Chen1, Zhuozhi Dai6, and Weixiong Fan1
1Meizhou People's Hospital, Meizhou, China, 2First Affiliated Hospital of Shantou University Medical College, Shantou, China, 3GE Healthcare, Guangzhou, China, 4Siemens Healthineers, Shanghai, China, 5Siemens Healthineers, Guangzhou, China, 6Shantou Central Hospital, Shantou, China
This study developed and validated a point-based scoring system (PSS) for stratifying the axillary lymph node (ALN) metastasis risk of breast cancer (BC) based on preoperative clinicopathological and MRI features compared with MRI-reported ALN status model and to explore its prognostic significance. The PSS in our study provides an easy tool for surgeons to assess breast cancer patients' risk for ALN metastasis prior to surgery. And the results showed that PSS had a relatively better performance than MRI-reported ALN status model (P=0.045),with a higher AUC, accuracy, and specificity, suggesting that PSS can be routinely used in axillary nodal staging.
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