Abstract #4265

A risk stratification scoring system for predicting axillary lymph node metastasis in breast cancer using multiparametric MRI

Xiaofeng Chen¹, Jiada Yang¹, Nina Fan¹, Zhiqi Yang¹, Ruibin Huang², Yue Li¹, Cuixia Wan¹, Junhao Gong¹, Yuting Liao³, Guijin Li⁴, Mengzhu Wang⁵, Fengyan Cheng¹, Xiangguang Chen¹, Zhuozhi Dai⁶, and Weixiong Fan¹

¹Meizhou People's Hospital, Meizhou, China, ²First Affiliated Hospital of Shantou University Medical College, Shantou, China, ³GE Healthcare, Guangzhou, China, ⁴Siemens Healthineers, Shanghai, China, ⁵Siemens Healthineers, Guangzhou, China, ⁶Shantou Central Hospital, Shantou, China

Synopsis

This study developed and validated a point-based scoring system (PSS) for stratifying the axillary lymph node (ALN) metastasis risk of breast cancer (BC) based on preoperative clinicopathological and MRI features compared with MRI-reported ALN status model and to explore its prognostic significance. The PSS in our study provides an easy tool for surgeons to assess breast cancer patients' risk for ALN metastasis prior to surgery. And the results showed that PSS had a relatively better performance than MRI-reported ALN status model (P=0.045),with a higher AUC, accuracy, and specificity, suggesting that PSS can be routinely used in axillary nodal staging.

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