Abstract #4274

Mean Apparent Propagator-MRI: A Novel Diffusion-Based Approach for Quantitative Assessment of Tumor-Stromal Ratio in Breast Carcinoma

Xiang Zhang¹, Wei Jiang¹, Mengzhu Wang², Zehong Yang¹, Xu Yan², Guang Yang³, Chunping Mao¹, and Jun Shen¹

¹Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China, ²MR Scientific Marketing, Siemens Healthineers, Guangzhou, China, ³Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, China

Synopsis

Mean apparent propagator (MAP)-MRI establishes a robust analytical framework based on the random motion distribution of natural water molecules. This study investigated the application of quantitative parameters derived from MAP-MRI in patients with breast cancer and determined whether MAP-MRI can be adopted as a better method than apparent diffusion coefficient (ADC) from conventional DWI to preoperative diagnosis tumor-stromal ratio. The results suggested that quantitative assessment with MAP-MRI showed superior predictive performance than conventional DWI for preoperative diagnosis of tumor-stromal ratio in patients with breast cancer.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.