Plenty of studies have reported correlations between the tissue pathological changes and abnormal T1 value. However, T1 mapping pulse sequences often suffer from the B1 inhomogeneity and long scan time. To improve the time efficiency without leading to the worse robustness to B1 inhomogeneity, we develop an accelerated MPRAGE-based 3D T1 mapping method by using SPGR steady state. Our proposed method is demonstrated in phantom experiments and the preliminary in-vivo brain scan.
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