Gd-EOB-DTPA has been widely used in liver MR imaging for the evaluation of hepatic lesion, whereas, the long intervals between the dynamic enhanced imaging and hepatobiliary phase imaging usually influence patient throughput. Notably, the adjustment of diffusion weighted imaging (DWI) sequence’s scanning order from pre-contrast to post-contrast is crucial to overcome this limitation. However, few studies have investigated the apparent diffusion coefficient (ADC) values that at low and high b values should be affected, respectively, thus, we aimed to prospectively determine whether DWI at both low and high b-values should be affected before and after gadoxetic acid-enhanced MR imaging.
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