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Abstract #4368

RF Coil design for improving human liver fat quantification in a portable single-side MR system

Shiwei Yang1, Xiao Chen2, Shuen Chen1, Hai Luo2, Yue Zhao2, Ziyue Wu2, and Zhiyong Zhang1
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, Shanghai, China, 2Wuxi Marvel Stone Healthcare Co. Ltd., Wuxi, Jiangsu, China, Wuxi, China


Earlier diagnosis of non-alcoholic fatty liver disease (NAFLD) becomes important to prevent the disease progression. Recently, a low-cost portable MR system was developed as a point-of-care screening tool for in vivo liver fat quantification. However, the subcutaneous fat may confound the live fat quantification, particularly in the NAFLD susceptible population. In this work, we propose a novel RF coil design composed of a main target coil sandwiching a set of “saturation” coil to improve human liver fat quantification. We demonstrate the capability and effectiveness of the novel RF design in phantom experiments as well as in-vivo liver scans.

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