Maps of the contrast agent concentration over time in mouse brains upon intraperitoneal administration were obtained by a dynamic MRI technique. The mice had different degrees of contrast agent accumulation clearly distinguishable on the maps with a particular distribution resembling the pathways of the glymphatic system. The average brain concentration computed 2 hours post contrast agent administration correlates with the gadolinium dosage in the brain by inductively coupled plasma mass spectroscopy proving that quantification is feasible although the signal analysis can be improved.
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