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Abstract #4415

CEST and ZAP Measurements of the Abdominal Organs

Vadim Malis1, Jirach Kungsamutr2, Won Bae1, Xiaowei Zhang1, Yoshimori Kassai3, and Mitsue Miyazaki1
1Radiology, UC San Diego, San Diego, CA, United States, 2Bioengineering, UC San Diego, San Diego, CA, United States, 3Canon Medical Systems Corp., Tochigi, Japan

Synopsis

Chemical exchange saturation transfer (CEST) is a molecular imaging technique for specific exchange of hydroxy (-OH, ~1.0 ppm), amine (-NH2, ~2 ppm), and amide (-NH, ~3.5 ppm), whereas ZAP is overall exchange protons of relatively free exchange protons (T2,f) and restricted protons (T2,r) from a wide frequency range of +/– 100 kHz. Combining CEST and ZAP to measure qualitative values of abdominal organ is aiming to be established.

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