Abstract #4438

Free-breathing Fully Ungated 3D Cardiac T2* MR Mapping using a Low-Rank Tensor Framework

Xingmin Guan^1,2, Hsin-Jung Yang¹, Zhehao Hu^2,3, Nan Wang⁴, Anthony Christodoulou¹, Behzad Sharif⁵, Debiao Li¹, and Rohan Dharmakumar^2,5

¹Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²University of California, Los Angeles, Los Angeles, CA, United States, ³University of Southern California, Los Angeles, CA, United States, ⁴Stanford University, Stanford, CA, United States, ⁵Indiana University, Indianapolis, IN, United States

Synopsis

A 3D fully ungated, free breathing cardiac T2* technique was developed using a low-rank tensor framework. An animal model with iron-oxide contrast-enhanced studies was used to test and validate the proposed technique. T2* images reconstructed from the proposed approach showed better image quality than those from conventional 2D T2* imaging approach. Excellent agreement of septal T2* was found between the proposed approach and conventional 2D approach. Our findings show that the proposed approach can accurately characterize T2* of myocardium under baseline and during iron overload conditions.

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