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Abstract #4438

Free-breathing Fully Ungated 3D Cardiac T2* MR Mapping using a Low-Rank Tensor Framework

Xingmin Guan1,2, Hsin-Jung Yang1, Zhehao Hu2,3, Nan Wang4, Anthony Christodoulou1, Behzad Sharif5, Debiao Li1, and Rohan Dharmakumar2,5
1Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2University of California, Los Angeles, Los Angeles, CA, United States, 3University of Southern California, Los Angeles, CA, United States, 4Stanford University, Stanford, CA, United States, 5Indiana University, Indianapolis, IN, United States


A 3D fully ungated, free breathing cardiac T2* technique was developed using a low-rank tensor framework. An animal model with iron-oxide contrast-enhanced studies was used to test and validate the proposed technique. T2* images reconstructed from the proposed approach showed better image quality than those from conventional 2D T2* imaging approach. Excellent agreement of septal T2* was found between the proposed approach and conventional 2D approach. Our findings show that the proposed approach can accurately characterize T2* of myocardium under baseline and during iron overload conditions.

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