Quantitative Susceptibility Mapping for Chamber Blood Oxygenation in Pulmonary Hypertension: Validation using Right Heart Catheterization
Jiahao Li1,2, Katherine Tak3, Rachel Meier3, Pablo Villar-Calle3, Justin Johannesen3, Jiwon Kim3, Yi Wang1,2, Jonathan W. Weinsaft3, and Pascal Spincemaille2
1Biomedical Engineering, Cornell University, New York, NY, United States, 2Radiology, Weill Cornell Medicine, New York, NY, United States, 3Medicine, Weill Cornell Medicine, New York, NY, United States
Pulmonary hypertension (PH) is a progressive and life shortening disorder with increased differential blood oxygen saturation (ΔSaO2) between right and left heart. In this prospective study, we acquired cardiac QSM from patients undergoing clinically indicated right heart catheterization (RHC) for assessment of known or suspected PH. ΔSaO2 estimated from QSM aligned well with RHC oxygenation data, showing QSM as a non-invasive CMR technique can be applied to clinically evaluate heart chamber oxygenation quantification in PH.
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