Meeting Banner
Abstract #4454

MR imaging of stroke rats using CEST with an Average Saturation Efficiency Filter (ASEF)

Julius Juhyun Chung1 and Tao Jin1
1University of Pittsburgh, Pittsburgh, PA, United States


Average Saturation Efficiency Filter (ASEF) is a fast and intuitive technique for achieving CEST imaging with improved sensitivity removing fast exchanges and semi-solid MT background with minimal loss to sensitivity. Our results in MCAO rodents showed that it can detect the ischemic lesion from CEST signal contrasts at 3.6, 2.6, and 2 ppm which may provide different metabolic-related information with higher sensitivity to 3-point measurement at 3.6 ppm and comparable contrast. Its low requirement on number of imaged signals also opens up possibilities for dynamic imaging or signal averaging.

This abstract and the presentation materials are available to members only; a login is required.

Join Here