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Abstract #4543

Reference value of ascending aorta global longitudinal strain by cardiovascular magnetic resonance feature tracking

HongZhou Zhang1,2, Shuang Leng1,3, Ru-San Tan1,3, Ping Chai4,5, Jennifer Bryant1,3, Lynette Teo5,6, Ching Ching Ong4,5, Angela S. Koh1,3, Wen Ruan1, James W. Yip4,5, Ju Le Tan1,3, and Liang Zhong1,3
1National Heart Centre Singapore, Singapore, Singapore, 2Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China, 3Duke-NUS Medical School, Singapore, Singapore, 4National University Heart Centre, Singapore, Singapore, 5Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 6National University Hospital, Singapore, Singapore


This study aimed to introduce a novel parameter—aorta (AO) global longitudinal strain (GLS)—for AO stiffness assessment by semi-automated feature tracking approach with standard cine cardiovascular magnetic resonance (CMR). The data demonstrated excellent intra and inter-observer variability of AO GLS of 4.4% and 5.0%, respectively. AO GLS was significantly negatively associated with age. The mean AO GLS was greater in females (10.1±3.5% versus 8.1±2.7%, P<0.001). The AO GLS decreased by 1.68% in females and 1.32% in males per decade respectively. Age was an independent predictor of the AO GLS in both males and females.

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