Abstract #4548

Evaluation of the Instability of Intracranial Aneurysms Wall by Dynamic Contrast-enhanced Magnetic Resonance Imaging and Vessel Wall Imaging

Qichang Fu¹, Yi Zhang¹, Jingliang Cheng¹, Sheng Guan², and Chengcheng Zhu³

¹Department of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²Department of Interventional Neuroradiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ³Department of Radiology, University of Washington, Washington, WA, United States

Synopsis

This study used DCE-MRI and VWI to explore the value of K^trans and aneurysm wall enhancement (AWE) in screening UIAs instability. Eighty-two patients were enrolled, including 51 patients with stable IAs and 31 patients with unstable IAs. All patients completed examinations based on a 3.0T Siemens Prisma magnetic resonance. Multivariate logistic regression revealed that AWEP (OR, 4.1; 95% CI, 2.06 to 8.16; P < 0.001) and K^trans (OR, 2.77; 95% CI, 1.49 to 5.17; P = 0.01) were the only independent factors associated with unstable UIAs. Both K^trans and AWEP were independent risk factors for the unstable state of UIAs.

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