Evaluation of the Instability of Intracranial Aneurysms Wall by Dynamic Contrast-enhanced Magnetic Resonance Imaging and Vessel Wall Imaging
Qichang Fu1, Yi Zhang1, Jingliang Cheng1, Sheng Guan2, and Chengcheng Zhu3
1Department of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2Department of Interventional Neuroradiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 3Department of Radiology, University of Washington, Washington, WA, United States
This study used DCE-MRI and VWI to explore the value of Ktrans and aneurysm wall enhancement (AWE) in screening UIAs instability. Eighty-two patients were enrolled, including 51 patients with stable IAs and 31 patients with unstable IAs. All patients completed examinations based on a 3.0T Siemens Prisma magnetic resonance. Multivariate logistic regression revealed that AWEP (OR, 4.1; 95% CI, 2.06 to 8.16; P < 0.001) and Ktrans (OR, 2.77; 95% CI, 1.49 to 5.17; P = 0.01) were the only independent factors associated with unstable UIAs. Both Ktrans and AWEP were independent risk factors for the unstable state of UIAs.
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