Abstract #4552

The Value of Free-breathing 4D-Flow MRI in Children with Extrahepatic Portal Venous Obstruction: A Preliminary Study

Huiying Wu¹, Ning Zhou¹, Zhe Wen², Lianwei Lu¹, Mingjie Zhang¹, Fuyu You², Tao Liu², Yunzhu Wu³, and Xiaochun Zhang*¹

¹Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou, China, ²Pediatric Surgery, Guangzhou Women and Children’s Medical Center, Guangzhou, China, ³MR Scientific Marketing, Siemens Healthineers, Guangzhou, China

Synopsis

This preliminary study has investigated the feasibility of free-breathing 4D-flow MRI to evaluate portal hemodynamics in children with EHPVO. Free-breathing 4D-flow MRI is feasible and hopeful for the comprehensive 3D visualization and quantification of portal vein flow dynamics in 14 children and the peak velocity had similar diagnostic efficiency to ultrasound in our study. In the future, we intend to compare 4D-flow parameters with intraoperative manometry of the portal vein system and use the noninvasive radionics methodology to estimate portal vein hemodynamics in children.

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