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Abstract #4552

The Value of Free-breathing 4D-Flow MRI in Children with Extrahepatic Portal Venous Obstruction: A Preliminary Study

Huiying Wu1, Ning Zhou1, Zhe Wen2, Lianwei Lu1, Mingjie Zhang1, Fuyu You2, Tao Liu2, Yunzhu Wu3, and Xiaochun Zhang*1
1Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou, China, 2Pediatric Surgery, Guangzhou Women and Children’s Medical Center, Guangzhou, China, 3MR Scientific Marketing, Siemens Healthineers, Guangzhou, China


This preliminary study has investigated the feasibility of free-breathing 4D-flow MRI to evaluate portal hemodynamics in children with EHPVO. Free-breathing 4D-flow MRI is feasible and hopeful for the comprehensive 3D visualization and quantification of portal vein flow dynamics in 14 children and the peak velocity had similar diagnostic efficiency to ultrasound in our study. In the future, we intend to compare 4D-flow parameters with intraoperative manometry of the portal vein system and use the noninvasive radionics methodology to estimate portal vein hemodynamics in children.

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