In our study, we conducted a prospective study to investigate the subclinical cardiotoxicity by serial cardiovascular magnetic resonance (CMR) in patients receiving immune checkpoint inhibitor (ICI). Some functional parameters and global strains of bi-ventricles revealed significant decrease at the early stage on ICI therapy, and ejection fraction as well as global strain values of both ventricles all showed a decline trend. Tissue characterization is an extra advantage of CMR technique. While in our study, parameters (T1 mapping, T2 mapping and late gadolinium enhancement) regarding tissue characterization of global myocardium showed no significant differences, compared with baseline data.
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