This study investigated the relationship between the geometry of vertebra-basilar system and hemodynamic measurements and presence of BA plaques. We found that geometric measurements and most hemodynamic features were significantly correlated with the occurrence of BA plaque (mean curvature, r=0.368; NOR-TAWSS-NF, r=-0.312; SAR-OSI-NF, r=0.290; NOR-TAWSS-nNF, r=-0.387; NOR-OSI-nNF, r=0.440). There were significant differences in mean curvature, hemodynamic characteristics of Newtonian flow and non-Newtonian flow models between patients with and without BA plaque. Our study indicated that geometric features and non-Newtonian flow model-based hemodynamic measurements are risk factors of BA plaque.
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