Abstract #4587

The impact of hemodynamic patterns and geometric features of vertebra-basilar system on atherosclerotic plaque occurrence

Rui Shen¹, Hualu Han¹, Jinmei Zheng², Huiyu Qiao¹, Zihan Ning¹, Xinyu Tong³, Yunjing Xue⁴, and Xihai Zhao¹

¹Center for Biomedical Imaging Research, Tsinghua University, Beijing, China, ²Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China, ³Department of Biomedical Engineering, School of Life and Science, Beijing Institute of Technology, Beijing, China, ⁴Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China

Synopsis

This study investigated the relationship between the geometry of vertebra-basilar system and hemodynamic measurements and presence of BA plaques. We found that geometric measurements and most hemodynamic features were significantly correlated with the occurrence of BA plaque (mean curvature, r=0.368; NOR-TAWSS-NF, r=-0.312; SAR-OSI-NF, r=0.290; NOR-TAWSS-nNF, r=-0.387; NOR-OSI-nNF, r=0.440). There were significant differences in mean curvature, hemodynamic characteristics of Newtonian flow and non-Newtonian flow models between patients with and without BA plaque. Our study indicated that geometric features and non-Newtonian flow model-based hemodynamic measurements are risk factors of BA plaque.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.