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Abstract #4651

Detection of early metastatic lymph nodes using inflow-based vascular-space-occupancy (iVASO) MR imaging

Yuankui Wu1, Liuji Guo1, Jun Hua2,3, Xiaomin Liu1, Yikai Xu1, and Kan Deng4
1Department of Medical Imaging, Nanfang Hospital, Southern Medical University, Guangzhou, China, 2Neurosection, Division of MRI Research, Department of Radiology,, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 3F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, 4Philips Healthcare, Guangzhou, China


Accurate preoperative evaluation of lymph nodes (LNs) involvement is of vital importance for clinical decisions and optimizing individual treatment regimens. Related studies showed elevated perfusion at the level of capillary in metastatic LNs. Inflow-based vascular space occupancy (iVASO) is a novel and noninvasive perfusion technology that can provide absolute blood volume of precapillary arterioles (arteriolar blood volume, BVa). In this study, the potential value of BVa in detecting metastatic LNs was investigated. The results showed that the BVa might have the potential to detect early metastases within lymph nodes.

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