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Abstract #4700

Ultra-Fast T1-Weighted Imaging with Wave-CAIPI MPRAGE for Clinical Pediatric Brain MR imaging: A Prospective Quantitative Assessment Study

Yung-Chieh Chen1, Duen-Pang Kuo1,2, and Cheng-Yu Chen1
1Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan, 2Translational Imaging Research Center, Taipei Medical University Hospital, Taipei, Taiwan

Synopsis

Morphologic neuroimaging in children can be challenging and time-sensitive during routine clinical imaging workflow due to patient discomfort, susceptibility to motion, and frequent need of sedation. Our study quantitatively assessed the imaging performance of ultra-fast T1 3D magnetization-prepared rapid acquisition gradient echo (MPRAGE) using wave-controlled aliasing with parallel imaging (wave-CAIPI) sequence for accelerated pediatric brain MR imaging via whole brain wide analysis under different MR imaging parameter settings with and without contrast administration. Our results show that wave-CAIPI can deliver comparable image quality to standard MPRAGE with significantly reduced scan times with optimized imaging parameters.

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