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Abstract #4700

Ultra-Fast T1-Weighted Imaging with Wave-CAIPI MPRAGE for Clinical Pediatric Brain MR imaging: A Prospective Quantitative Assessment Study

Yung-Chieh Chen1, Duen-Pang Kuo1,2, and Cheng-Yu Chen1
1Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan, 2Translational Imaging Research Center, Taipei Medical University Hospital, Taipei, Taiwan


Morphologic neuroimaging in children can be challenging and time-sensitive during routine clinical imaging workflow due to patient discomfort, susceptibility to motion, and frequent need of sedation. Our study quantitatively assessed the imaging performance of ultra-fast T1 3D magnetization-prepared rapid acquisition gradient echo (MPRAGE) using wave-controlled aliasing with parallel imaging (wave-CAIPI) sequence for accelerated pediatric brain MR imaging via whole brain wide analysis under different MR imaging parameter settings with and without contrast administration. Our results show that wave-CAIPI can deliver comparable image quality to standard MPRAGE with significantly reduced scan times with optimized imaging parameters.

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