Characterizing diffusion properties on extremities of patients with lymphedema by MRI
Yeefan Lee1,2, Kuan-Hung Cho3, Chih-Hsing Tang2, Chia-Wen Chiang3, Shih-Yen Lin4, Chen-Hsiang Kuan5, Chien-Yuan Lin6, Hsiao-Ling Lee6, and Li-Wei Kuo3
1Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan, 2Department of Medical imaging, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan, 3Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli County, Taiwan, 4Department of Computer Science, National Yang Ming Chiao Tung University, Hsinchu, Taiwan, 5Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan, 6GE Healthcare, Taipei, Taiwan
Lymphedema is defined as accumulation of fluid and fibroadipose tissues due to disruption of lymphatic flow. Our results demonstrate a significant difference of diffusion measures between lymphedema and normal groups. DKI and DTI derivatives have similar tendency when comparing lymphedema patients with healthy subjects. The diffusion properties may aid the diagnosis of lymphedema and have the potential for evaluating the severity in postoperative follow-up.
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