B0 shimming for 7T cardiac T2*-weighted MRI in large animals: practical demands and hardware limitations.
Maxim Terekhov1, David Lohr1, Michael Hock1, Maya Bille1, Julia Aures1, Ibrahim A. Elabyad1, Florian Schnitter2, Wolfgang Bauer2, Ulrich Hofmann2, and Laura M. Schreiber1
1Chair of Cellular and Molecular Imaging, Comprehensive Heart Failure Center, University Hospital Würzburg, Comprehensive Heart Failure Center, Wuerzburg, Germany, 2Department of Internal Medicine I, Cardiology, University Hospital Würzburg, Wuerzburg, Germany
Cardiac MRI with T2*-contrast at 7T is of particular interest because it is highly sensitive to cardiac tissue alterations after myocardial injury. A reliable T2*-contrast quantification and usage for tissue characterization require minimization of the inhomogeneity of the B0-field in the heart. In this work, we analyzed the B0-conditions achievable in longitudinal T2* measurements in the hearts of domestic pigs which during the experiment grew from 30 to 90 kg. B0 distribution statistics were summarized for the maps of individual slices. Demands on the 7T-scanners B0-shimming hardware (up to 3rd-order spherical harmonics) were analyzed.
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