Meeting Banner
Abstract #4822

Volumetric ultrasound hyperthermia treatment using the ExAblate body MR-guided Focused Ultrasound (MRgFUS) system

Kisoo Kim1, Muhammad Zubair2, Chris J Diederich2, and Eugene Ozhinsky1
1Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Radiation Oncology, University of California, San Francisco, San Francisco, CA, United States


Hyperthermia refers to a cancer treatment by elevating tissue temperature to 40-45 °C. Hyperthermia can be achieved by clinical MRgFUS system, allowing real-time temperature monitoring for the precise control of hyperthermia heating. Currently the ExAblate is MR-guided FUS ablation system with the largest installation worldwide, however, requires advanced beamforming strategies for volumetric hyperthermia. This study proposed electronic beam steering, multi-focal patterns, and sector-vortex beamforming approaches in conjunction with partial array activation and was evaluated in biothermal simulations and phantom experiments. This study demonstrated the feasibility of sustained large volume heating with MR thermometry feedback using the ExAblate body system.

This abstract and the presentation materials are available to members only; a login is required.

Join Here