Abstract #4861

Highly accelerated 4D flow MRI using compressed sensing in type B aortic dissection

Ozden Kilinc¹, Stanley Chu¹, Elizabeth K. Weiss^1,2, Justin Baraboo^1,2, Anthony Maroun¹, Ning Jin³, Kelvin Chow^1,4, Xiaoming Bi⁴, Rachel Davids⁴, Chris Mehta⁵, S. Chris Malaisrie⁵, Andrew Hoel⁶, Michael Markl^1,2, and Bradley D. Allen¹

¹Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ²Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States, ³Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Cleveland, OH, United States, ⁴Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Chicago, IL, United States, ⁵Division of Cardiac Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ⁶Division of Vascular Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States

Synopsis

4D flow MRI is an established quantitative MR imaging technique for evaluating complex blood flow patterns. However, clinical applications of standard 4D flow MRI technique is limited by long scan times associated with multidimensional imaging. Compressed sensing (CS) acceleration can significantly reduce scan time through dramatic data undersampling, but it is not clear how this undersampling impacts assessment of flow patterns in type B aortic dissection (TBAD). In this study, we investigate performance of highly accelerated CS 4D flow MRI at two different acceleration factor levels (R=7.7 and 10.2) to evaluate aortic flow dynamics in volunteers and patients with TBAD.

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