In a cross-sectional study of hypertension and its effects on brain connectivity, graph theory can be used to show cerebral blood flow connectivity differences between normotensive (n=32) and hypertensive (n=37) subjects. We obtain adjacency matrices from processed arterial spin labelling scans which can be used to determine several quantifications based on graph theory analysis. We find that normotensive subjects exhibit higher small-worldness and global efficiency (σ = 3.30 and Eglob = 0.73) compared to hypertensive subjects (σ = 1.82 and Eglob = 0.46). This trend continues for nearly all thresholding values and implies a measurable perfusion difference between the groups.
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